Two Buildings at a Pharmaceutical Production Site in Belgium: Expansion and Renovation by GSE

A Pharmaceutical Site in the midst of Industrial Scaling Up

The project carried out for KANEKA Eurogentec in Seraing is part of a major strategic evolution of the site, aimed at transitioning the production of very high value-added biomolecules from an industrial demonstration phase to full-scale industrial production. This scaling up involves a profound transformation of the existing infrastructure to enable the development and production of innovative solutions at a higher capacity. The main challenge lies in the ability to support this transition while maintaining the site’s operations—which include offices and active laboratories—in an environment where production and research constraints must coexist at all times.

Seamless Integration of Innovative Pharmaceutical Processes

The project is based on the integration of an innovative pharmaceutical process, developed in parallel with the building’s design and construction. This unique aspect requires particularly precise control of the interfaces between the building and the process equipment, as these interfaces are numerous and critical to ensuring the site’s overall performance. The scope of work thus included coordinating all process equipment to ensure its seamless integration into the new infrastructure and the renovated buildings. This approach was essential to address the specific constraints associated with biomolecule development and the gradual scaling up of clinical batch production, while ensuring the continuity and reliability of industrial operations.

Highly secure environments that comply with pharmaceutical standards

The project was designed to meet the pharmaceutical industry’s most stringent requirements, with a particular focus on the safety of people and products. The facilities include 1,000 m² of ISO 7 and ISO 8-classified laboratories, as well as biosafety level 2 laboratories, ensuring controlled environments suited to the site’s sensitive activities. The entire facility also complies with Good Manufacturing Practices (GMP) requirements, ensuring a high level of quality and regulatory compliance. The design and construction process is further supported by a full BIM approach—from the design phase through to operations—combined with a BMS 2.0 system, enabling optimized facility management and enhanced control over operating conditions.