{"id":6958,"date":"2017-10-17T16:51:00","date_gmt":"2017-10-17T14:51:00","guid":{"rendered":"https:\/\/www.gsegroup.ro\/?post_type=realisation&#038;p=6958"},"modified":"2026-08-17T16:54:27","modified_gmt":"2026-08-17T14:54:27","slug":"sister","status":"publish","type":"realisation","link":"https:\/\/www.gsegroup.ro\/en\/realisation\/sister\/","title":{"rendered":"Sister"},"content":{"rendered":"\n<h1 class=\"wp-block-heading\">Production Facility in Italy: Constructed by GSE<\/h1>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-left\">A construction project carried out in an occupied facility with strict phasing constraints<\/h2>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">The project for SisTer, a subsidiary of the German group Fresenius SE &amp; Co. KGaA, was carried out under particularly challenging conditions in an occupied facility, requiring business operations to continue alongside the construction work. This situation called for rigorous site management and precise phasing of the work to minimize any disruption to existing production.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">The tight completion deadline further heightened these coordination requirements, while also necessitating continuous adaptation to changes in client expectations and the project specifications. The entire project was thus progressively defined and adjusted, with a constant focus on finding technical solutions compatible with operational constraints and the sensitive environments of the cleanrooms.<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-left\">Structural Reinforcement and Integration of New Infrastructure into the Existing Structure<\/h2>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">The project includes a significant component of structural reinforcement of the existing building, notably through its retrofitting to meet seismic standards, in order to ensure its compliance with regulatory requirements and its long-term durability. This work was complemented by the construction of a new structure directly integrated into the existing building, relying on the installation of deep foundations and a prefabricated structure.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">This work was carried out under constrained conditions, taking into account legal obligations related to neighborhood issues, while adhering to the quality requirements specific to the sector, particularly GMP procedures. Collectively, these interventions enabled the industrial facility to be adapted to new production requirements while ensuring the long-term structural safety of the building.<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-left\">Technical Performance, Controlled Environment, and Continuous Production Requirements<\/h2>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">The facility was designed to meet high technical standards and support continuous production, operating 24 hours a day, 7 days a week within a temperature range of -15 \u00b0C to +40 \u00b0C. The facilities include a filtered air system with a capacity of 120,000 m\u00b3\/h, ensuring that strict environmental conditions suitable for biomedical activities are maintained.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">The infrastructure also includes significant energy capacity, with an installed power capacity of 1.5 MWp and a cooling capacity of 1.3 MWp, ensuring the site\u2019s overall performance. This equipment supports controlled environments, including ISO 8 cleanrooms, a laboratory, a decontamination room, and a packaging area\u2014all essential for meeting the sector\u2019s production and quality requirements.<\/p>\n","protected":false},"featured_media":6733,"menu_order":0,"template":"","categories-pays":[],"categorie-realisation":[32],"type-batiment":[],"class_list":["post-6958","realisation","type-realisation","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>SisTer: Construction of a Production Facility in Italy - GSE Romania<\/title>\n<meta name=\"description\" content=\"The project for SisTer, a subsidiary of the German group Fresenius SE &amp; Co. 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